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Importantly, these receptors were found to happen to be activated by a variety of endogenous opioids at a focus similar to that noticed for activation and signaling of classical opiate receptors. In turn, these receptors were discovered to acquire scavenging activity, binding to and decreasing endogenous amounts of opiates available for binding to

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Importantly, these receptors ended up observed to have already been activated by an array of endogenous opioids at a focus much like that observed for activation and signaling of classical opiate receptors. Subsequently, these receptors were being uncovered to possess scavenging exercise, binding to and decreasing endogenous amounts of opiates read

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